Detroit will clash with the Philadelphia Eagles on Sunday Night Football, a matchup that could become a critical tiebreaker in the race for the NFC’s No. 1 seed. A Lions win alone would be huge, but it always helps when a little extra cash comes with it. After going a perfect 3-0 last week, improving my season record to 10-5, I’m rolling into this matchup with three more picks that I believe have a strong chance to hit.

Before diving into the bets, some significant news broke Friday: the Lions are placing tight end Sam LaPorta on injured reserve, sidelining him for at least four games. It’s a major blow to Detroit’s offense.

Lions Money Line (+124)

We’ll start with my boldest pick. The Lions are on the road, taking on the defending Super Bowl champions, and they’ll be without several key contributors, including LaPorta, Terrion Arnold and Kerby Joseph. On paper, that’s a tall task.

But Detroit has been here before. Before the bye week, the Lions were missing multiple starters against the Tampa Bay Buccaneers, and they handled business convincingly in a 24-9 win. Philadelphia is a tougher challenge, but I’m not sold on the Eagles’ offense. They scored just 10 points last week against the Packers and have been inconsistent throughout the season.

If Detroit can reach 25 or more points, I believe they put themselves in position to win. The Lions have also been outstanding in primetime under Dan Campbell, holding a 13-3 record. They are 2-1 in primetime this year, with their only loss coming on Sunday night against the Chiefs.

Give me the Lions to rise to the moment and shock the champs.

Jahmyr Gibbs Over 13.5 Rush Attempts (-115)

This is my favorite bet of the week. Gibbs has failed to hit this number in four games this season, but all signs point to him clearing it on Sunday night.

In all but one game this year, the Eagles have allowed the opposing lead running back to record at least 15 rushing attempts. Teams that have beaten Philadelphia — most notably the Broncos and Giants — did so by controlling the clock and leaning heavily on the ground game. In both of those wins, the lead backs finished with more than 20 attempts.

Philadelphia’s run defense is average at best, and Detroit can exploit it. With LaPorta now out, the Lions are likely to lean even more on Gibbs, both in volume and versatility. This number feels very reachable.

Jahmyr Gibbs Anytime Touchdown (-125)

This is one of the better values you’ll get for a Gibbs touchdown all season.

The Eagles allow the sixth-worst rushing touchdown rate in the league at 1.2 per game. Over their last three games, they’ve given up at least one rushing score in each matchup. They’ve also allowed three receiving touchdowns to running backs this year, averaging 0.3 per game.

Gibbs has been electric in 2025, scoring in all but two games. He’s recorded multiple touchdowns in three different games and has proven he can score from anywhere on the field.

Given his usage, explosiveness and Detroit’s injury situation, I’m backing him to find the end zone again.

Last week, a parlay of all three of my picks would have cashed, and this week the combined odds sit at +345 — meaning a $10 bet would return $34.50. If you’re looking to pad your wallet, look no further than Jahmyr Gibbs and the Detroit Lions on Sunday night.