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    Savanah Tujague
    Savanah Tujague
    Nov 28, 2025, 14:00
    Updated at: Nov 28, 2025, 14:00

    Two physical titans clash on Thanksgiving weekend. Can the 49ers reclaim dominance against Cleveland's suffocating defense?

    Thanksgiving weekend is here, the crown jewel of the NFL regular season. NFL games, cold weather football, playoff races tightening, and nothing but time to sit, eat, and watch contenders prove themselves. And tucked into one of the league’s best weekends of the year is a very random matchup: the San Francisco 49ers traveling to Cleveland to take on the Browns this Sunday.

    This game isn’t just another checkpoint on the schedule. It’s a measuring-stick moment for both teams.

    49ers: Looking to Reestablish Dominance

    San Francisco enters the weekend aiming to shake off the inconsistency that’s popped up over the last few weeks. Brock Purdy will look to rebound after his rough outing against Carolina. Christian McCaffrey remains the centerpiece of the attack, even after a quiet outing by his standards. Expect Kyle Shanahan to emphasize the run early, especially behind an offensive line that had standout performances from everyone all around but especially Dominick Puni and Trent Williams last week. The Niners will also need more from their receivers after multiple pass-catchers graded out poorly, something that cannot continue against a defense as aggressive as Cleveland’s.

    Defensively, San Francisco’s secondary will again rely on Ji’Ayir Brown and Malik Mustapha, who both shined last week. Their range and closing speed will be critical against Cleveland’s quick passing game. But the biggest question remains up front: can the defensive line generate consistent pressure without giving up explosive plays? The Browns’ offensive line is banged up, and this could be an opportunity for the Niners’ young interior defenders like Kalia Davis to leave a mark.

    Browns: Surviving Through Defense

    Cleveland continues to rely on its identity: a physical, suffocating defense headlined by Myles Garrett. If Garrett wreaks havoc early, this game could grind into the kind of low-scoring brawl the Browns thrive in.

    Offensively, Cleveland is still a week-to-week mystery. Injuries have forced them into a conservative approach, leaning on the run game and hoping for efficient quarterback play. But if they can avoid turnovers and stay ahead of the chains, they have the tools to frustrate the Niners.

    A Perfect Thanksgiving Weekend Matchup

    Thanksgiving weekend always delivers drama on and off the football field honestly, and the Niners @ Browns fits the vibe perfectly. This will be a matchup of two physical teams, two bruising defenses, and two fanbases with very different expectations. It’s the best weekend of the NFL season and because of that this matchup might get interesting.