The Milwaukee Brewers fell to the St. Louis Cardinals on Wednesday 5-1 at Busch Stadium in the fourth game of their five-game series. 

After Milwaukee won the first three games, Wednesday’s loss ruins its bid at the sweep and ends its four-game winning streak. 

Through multiple games in their winning streak, the Brewers had to work their way out of deficits to win games. On Wednesday, they simply could not make it happen.

In the bottom of the first inning, St. Louis attacked Kyle Harrison and the Milwaukee defense immediately. Harrison gave up a leadoff double to Masyn Winn before allowing a one-out RBI double to Jordan Walker that gave the Cardinals a 1-0 lead.

After striking out Nelson Velazquez, Harrison allowed another RBI double, this time to Alec Burleson. By the time the Brewers got out of the inning, they were facing a 2-0 deficit.

In the second and third innings, Harrison and the defense kept St. Louis from doing additional damage, but they could not mount a response on the offensive end. In the fourth, the Cardinals struck again.

After forcing Burleson into a groundout, Harrison gave up a solo home run to Jose Fermin. The Brewers got out of the inning after it, but now they had to make up three runs to get back in the game.

After the offense came up empty in the top of the fifth, manager Pat Murphy ended Harrison’s evening and went to his bullpen. Harrison went back to the dugout with a final line of four hits, three earned runs, and two strikeouts over four innings. He was also assessed the losing decision, marking only the second loss of his 2026 campaign.

Grant Anderson took over for Harrison, and the Cardinals were sent down in order. But once again, Milwaukee’s offense did not have an answer.

In the bottom of the sixth, St. Louis hit the Brewers again, and it ended up being much too great to overcome.

After Anderson gave up a leadoff single to begin the frame, he was able to record a strikeout before Murphy went to the bullpen again. This time, he called on Jared Koenig, and Burleson made Koenig pay immediately with a two-run home run.

At this point, Milwaukee was down 5-0, and time was running out. The Brewers would have needed a flurry of runs in a single inning to get back in the game, a task that was not beyond the capabilities of the offense.

All season, Milwaukee’s batting order has been able to put together a flurry of runs in one frame, and in the seventh inning, it demonstrated a pulse. After Garrett Mitchell hit a double and Luis Lara followed up with a single, Cooper Pratt drove Mitchell home via a sacrifice fly to finally get the Brewers on the board.

Subsequently, Joey Ortiz hit a two-out double, but Andrew Vaughn grounded out to end the inning. With six outs available at that point, the Brewers managed just one more hit, and they were handed the loss. Overall, they went 7-for-32 at the plate with nine strikeouts.

Milwaukee will try to conclude the series with a win when it faces St. Louis on Thursday at 6:45 p.m. CT.

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