Oct 8, 2026 1:42 AM

Scout upcoming Big 12 rivals, track the Red River Rivalry, and monitor conference powerhouses as the path to the postseason intensifies for the Cyclones.

Publisher Brad Schultz shares his thoughts on the ISU-BYU game.More Videos

Time is flying by, and Week 6 of the college football season is here with big conference matchups and rivalry games on the slate. And with Iowa State taking on BYU late Friday night, the opportunity to relax on your couch and take in the top games of Week 6 is very present. 

Here are a few games we think you should keep an eye on in Week 6:

Friday

Florida State Seminoles (3-2) vs. Louisville Cardinals (4-1)

Location: L&N Federal Credit Union Stadium in Louisville, KY 

Time/TV: 6:00 p.m. CDT on ESPN 

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A big ACC matchup on Friday night features both teams hoping to get a big conference win. Louisville wants to defend its home field, while Florida State is aiming for a big road victory to stay in the ACC race and keep head coach Mike Norvell's job. 

No. 20 Iowa Hawkeyes (4-1)  vs. Washington Huskies (3-2) 

Location: Husky Stadium in Seattle, WA 

Time/TV: 8:00 p.m. CDT on FOX or FS1 

If you're looking for a last-minute hate watch before Iowa State kicks off at 9:15 Iowa time, you'll probably want to watch this game. Iowa needs this win to stay in College Football Playoff contention after a disappointing loss to Ohio State last weekend, while Washington is desperate for any sort of a win after blowing a double-digit lead at USC. 

This game should help keep you awake before the Cyclones kick off. 

Saturday

Arizona Wildcats (3-1) vs. West Virginia Mountaineers (2-3)

Location: Mountaineer Field at Milan Puskar Stadium in Morgantown, WV

Time/TV: 11 a.m. CDT on FS1 

Cyclones fans will get to see two Big 12 opponents face off. West Virginia is looking to bounce back after last week's 45–42 loss to Iowa State, and Arizona hopes to build momentum before facing the Cyclones at home on October 24.

Texas A&M Aggies (4-1) vs. Missouri Tigers (4-1) 

Location: Faurot Field at Memorial Stadium in Columbia, MO 

Time/TV: 11 a.m. CDT on ESPN 

An early Saturday morning SEC showdown. Both teams with 4-1records, Missouri and Texas A&M seek crucial momentum against a tough conference slate. Getting a win keeps the winner at the top of the conference standings while helping their Playoff chances.

No. 1 Texas Longhorns (4-1) vs. Oklahoma Sooners (4-1) 

Location: Cotton Bowl Stadium in Dallas, TX 

Time/TV: 2:30 p.m. CDT on ABC 

The iconic Red River Rivalry returns to the Cotton Bowl for another exciting SEC battle. Both historic powerhouses come into Dallas at with a 4-1 record, with major conference standing and playoff positioning on the line. Expect an electric atmosphere as these rivals battle for the conference crown. 

Kansas Jayhawks (3-2) vs. No. 12 Utah Utes (4-1) 

Location: Rice-Eccles Stadium in Salt Lake City, UT 

Time/TV: 8:15 p.m. CDT on ESPN 

A late Saturday night Big 12 battle. Utah handed Iowa State a tough loss in their conference opener back in Week 4, and seeing how the Utes handle Kansas on home turf will give Cyclones fans a great sense of how the top tier of the Big 12 race is shaping up. 

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