The San Francisco 49ers made a clear investment in the trenches during the 2025 NFL Draft, selecting two defensive tackles within the first four rounds with the additions of Alfred Collins and CJ West in the second and fourth rounds.

Don’t be surprised if they double down again with the No. 27 overall pick in the upcoming draft.

The 49ers could once again turn their attention to the interior of the defensive line, a position that suddenly carries both short-term uncertainty and long-term intrigue.

San Francisco’s current starting defensive tackles are not under contract beyond the 2025 season. Jordan Elliott is set to become an unrestricted free agent in 2026, while Kalia Davis is trending toward restricted free agency.

That looming roster turnover makes the position one to watch closely, especially for a team that has consistently built its identity around defensive line dominance.

Alfred Collins is currently rehabbing after undergoing left shoulder surgery shortly after the season ended.

Lynch recently expressed optimism that Collins will be a full participant by the start of training camp in late July, but durability and depth remain key considerations.

The good news for San Francisco is that this year’s draft board could fall favorably.

There is no consensus top-20 locks at defensive tackle, meaning the 49ers could be in a position to select the highest-rated interior lineman on their board without trading up.

One intriguing option is Caleb Banks, a massive presence at 6-foot-6 and 335 pounds. Banks flashed disruptive ability during a strong 2024 campaign, recording 4.5 sacks.

However, his final college season was interrupted by a fractured foot that required surgery. While he returned to action in November, the 49ers would need to be confident in his medical evaluations before investing a first-round pick.

His size and upside are undeniable, but maintaining leverage at his height will be key at the next level.

Lee Hunter presents a different profile. Known primarily as a stout run defender, Hunter could immediately address an area where San Francisco was solid but not elite last season.

The 49ers allowed 4.3 yards per carry on the ground, leaving room for improvement in early-down situations. Hunter’s power at the point of attack stood out during Senior Bowl practices, where he consistently commanded attention.

While his pass-rush arsenal remains a work in progress, the tools are there for him to develop into a three-down force.

Then there’s Kayden McDonald, who brings a strong combination of size at 6-foot-3, 326 pounds and on-field production.

Coming off a season with 65 tackles, two forced fumbles, and three sacks, McDonald has shown he can anchor against the run while also pushing the pocket.

His physicality would fit seamlessly into the 49ers’ defensive philosophy.

At No. 27, San Francisco may not need to reach. If the board falls right, the 49ers could once again fortify the heart of their defense, ensuring their dominance up front remains intact for years to come.