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    Alec Elijah
    Nov 19, 2025, 13:28
    Updated at: Nov 20, 2025, 01:19

    For the first time since his trade in 2022, Christian McCaffrey faces off against the Carolina Panthers, who he played for during his first five and a half seasons in the NFL.

    This upcoming Monday has the potential to be not just an uber-competitive game featuring two of the top running backs in the NFL this season, but it could also be an emotional one for 49ers running back Christian McCaffrey.

    The Niners host the Carolina Panthers in what will be Christian McCaffrey's first game against his former team.

    OurSF49ers (@OurSf49ers) on X OurSF49ers (@OurSf49ers) on X How it started vs How it’s going: #49ers Christian McCaffrey plays The Panthers next Monday for the first time since being traded to the Niners 😮‍💨

    During his time with the Panthers, McCaffrey was already making a name for himself as one of the most talented backs in the NFL, displaying a keen ability to be more than a traditional running back. 

    Oct 16, 2022; Inglewood, California, USA; Carolina Panthers running back Christian McCaffrey (22) carries the ball against the Los Angeles Rams in the first half at SoFi Stadium. Mandatory Credit: Kirby Lee-Imagn Images

    His 2019 season was his most notable, with Carolina, as he captured his first Pro Bowl and First-team All-Pro nod of his career. He tallied 1,387 rushing yards and 1,005 receiving yards that season, becoming just the third player in NFL history to complete this tremendous feat. 

    Following that season, CMC was unable to recreate the magic he had displayed in the 2019 campaign, which ultimately forced both McCaffrey and the Panthers to agree that a change was necessary for both parties.

    Nov 16, 2025; Glendale, Arizona, USA; San Francisco 49ers running back Christian McCaffrey (23) looks on in the second half against the Arizona Cardinals at State Farm Stadium. Mandatory Credit: Matt Kartozian-Imagn Images

    That is when the 49ers struck gold by acquiring McCaffrey for a collection of draft picks mid-way through the 2022 season, and the rest has been history. 

    Since joining San Francisco, McCaffrey has been named to one more All-Pro First-Team and captured the NFL's Offensive Player of the Year trophy in 2023. 

    While this is not just the first time the 49ers face off against Carolina since 2022, this is also McCaffrey's first game against the Panthers, and as he is currently on pace for his second 1,000-yard rushing and receiving season, it is doubtful he will ease up on his former team. 

    Through the 49ers' 11 games, McCaffrey has logged 707 rushing yards and 732 receiving yards, with 11 total touchdowns so far. 

    Heading into Monday night's matchup, the 49ers sit  7-4 and third in the NFC West. If the season were to end this week, they'd be in the playoff picture, but with several weeks to go, every game from here on out remains crucial for San Francisco. 

    If I were a betting man, I would undoubtedly take his overs and assume that McCaffrey has an exceptional performance in store for the fans who once cheered him on so belovedly, and also for the 49er faithful that will be in attendance as well.