May 20, 2026 1:00 PM

From primetime clashes to a high-stakes Thanksgiving showdown, Mike Straw and Anthony Moeglin break down every matchup to forecast Buffalo’s path back to the AFC East throne.

Whose schedule predictions do you agree with more?

Mike Straw's
0%
Anthony Moeglin's
0%

The offseason work has started, and we know when the Buffalo Bills will take the field for the 2026 season. But how will the Bills do?

In the latest episode of the Bills Roundtable Podcast, hosts Mike Straw and Anthony Moeglin go through the 2026 Bills schedule game by game. From the matchups that interest us the most to the games where the Bills could be caught for a loss, there is no shortage of intrigue for a team many expect to be back at the top of the AFC East this year.

But how exactly will they do this year? We decided to start a new exercise. Throughout the year, on various episodes, we’ll go game-by-game and give our predictions. As major news breaks, like a new signing, a major injury, camp observations or otherwise, we’ll go through the schedule again to see how picks change, if at all.

Check out the first run through of the 2026 schedule below, and watch episode 32 of Bills Roundtable for the reasoning behind our picks.

2026 Buffalo Bills Schedule Predictions

Week 1: at Houston Texans

Straw: Loss / Moeglin: Win

Week 2: vs. Detroit Lions (Thursday Night Football)

Straw: Win / Moeglin: Win 

Week 3: vs. Los Angeles Chargers

Straw: Win / Moeglin: Win

Week 4: vs. New England Patriots

Straw: Win / Moeglin: Win

Week 5: at Los Angeles Rams (Monday Night Football)

Straw: Loss / Moeglin: Loss

Week 6: at Las Vegas Raiders

Straw: Win / Moeglin: Win

Week 7: Bye week

Week 8: vs. Baltimore Ravens

Straw: Loss / Moeglin: Win

Week 9: at Minnesota Vikings (Monday Night Football)

Straw: Win / Moeglin: Loss

Week 10: at New York Jets

Straw: Win / Moeglin: Win

Week 11: vs. Miami Dolphins

Straw: Win / Moeglin: Win

Week 12: vs. Kansas City Chiefs (Thanksgiving)

Straw: Loss / Moeglin: Loss

Week 13: at New England Patriots

Straw: Win / Moeglin: Win

Week 14: at Green Bay Packers (Sunday Night Football)

Straw: Win / Moeglin: Loss

Week 15: vs. Chicago Bears (Saturday)

Straw: Win / Moeglin: Win

Week 16: at Denver Broncos (Christmas)

Straw: Win / Moeglin: Win

Week 17: at Miami Dolphins

Straw: Win / Moeglin: Win

Week 18: vs. New York Jets

Straw: Win / Moeglin: Win

Final Record:

Straw: 13-4 / Moeglin: 13-4

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