Powered by Roundtable
Arizona Cardinals Injuries Going Into Division Matchup Against Los Angeles Rams cover image
bradkrejci@RoundtableIO profile imagefeatured creator badge
Brad Krejci
Dec 13, 2025
Partner

How are the Cardinals going to pull this off with so many injuries?

The Arizona Cardinals are going into a division matchup against a Super Bowl favorite, the Los Angeles Rams. Arizona has nothing to lose but are beaten and bruised with multiple injuries coming into this game.

Arizona's star quarterback Kyler Murray has officially been ruled out for the remainder of the season. Murray's future with the organization is still in question. Jacoby Brissett has been much more efficient since taking over the starting roll and will finish the season out as the starter. 

Trey Benson was the starting running back at the beginning of the season, has been ruled out for the Rams game as well. Emari Demercado has been picking up the slack in the absence of Benson but has also been ruled out for the matchup against the Los Angeles Rams.

Top wide receiver for the Cardinals, Marvin Harrison Jr. is being ruled out due to a heel injury he sustained in practice. My personal opinion is that Arizona does not want to risk any injuries to their number one offensive weapon, and this is a preventative measure. 

Arizona is also dealing with more than just the key offensive players being out this season. The defensive side of the ball has been going through their fair share of tragic loses.

Cornerback Max Melton is sadly ruled out with a heel injury. Walter Nolen III who leads the Cardinals in sacks this year at Defensive Tackle is ruled out as well with a knee injury. Joining Nolen III is his counterpart, Dadrion Taylor-Demerson is also out with a bad ankle.

Arizona is short-handed on both sides of the ball going into this game. Next man up is the mentality in Cardinal's locker room right now.