On paper, the Jacksonville Jaguars have another mismatch this week when they take on the last-place Tennessee Titans.

The Jaguars are rolling at 6-2, have a three-game lead in the AFC South, and have made a pair of the NFL’s most impactful trades at the deadline. 

Meanwhile, the Titans are 1-7 and have started yet another rebuild. Before the deadline, Tennessee traded Jeffery Simmons, arguably the league's best defensive tackle, and safety Amani Hooker, who leads the NFL with five interceptions. 

In addition to the trades, the Titans will also be without five injured starters against Jacksonville, including their two top rookies, WR Carnell Tate and LB Anthony Hill Jr.

The Jaguars have won their last two games by a combined score of 75-17 and are heavy favorites on the road against the Titans. 

Here are my five keys to a Jaguars victory over the Titans:

1. Don’t take the Titans lightly: The Jaguars are clearly the much better team in this AFC South showdown. Nothing could lead to a Jacksonville loss more than the Jaguars looking past the Titans. 

Head coach Liam Coen should have his team ready to go. The Jaguars could have easily looked past the overmatched Colts and Ravens the last two weeks. They didn’t, and it led to two dominant victories. 

2. Turnovers: The Jaguars' defense is terrific at forcing turnovers, and the team’s plus-9 turnover differential is the best in the NFL. 

As long as Jacksonville takes care of the ball on offense, it should be able to control the game and overwhelm the shorthanded Titans. If the defense can notch a couple of takeaways, even better. 

3. Get Bhayshul Tuten back on track: Tuten has enjoyed a breakout season as Jacksonville’s top running back, but had a rough time last week against Baltimore. Against the Ravens, Tuten rushed for only 29 yards on 12 carries and didn’t catch a pass for the first time all year. 

Tuten was a game-time decision last week after not practicing all week. He played, but it looked like he was operating at less than 100%. Now healthy, he should get back on track against a Titans defense that gives up about 124 yards per game on the ground. 

4. Stop Tony Pollard: Tennessee’s top RB is having a pretty solid season of his own. Pollard has already run for 595 yards and six TDs and averages 4.5 YPC.

Without Carnell Tate, the Titans will likely feed Pollard as many touches as he can handle. 

Jacksonville’s run defense fell from first in the NFL to fifth after allowing the Ravens to run for 172 yards. The Jaguars will be without their two biggest deadline acquisitions, DT Jordan Davis and safety Jessie Bates III. Everyone else on Jacksonville’s defense must step up to ensure there isn’t a repeat of last week. 

5. Get Brian Thomas Jr. involved: The Jaguars made the somewhat surprising decision not to trade BTJ at the deadline. 

Now the team must find a way to get the talented but struggling WR involved in the offense. Thomas has had his playing time significantly cut and has only one catch in the last four games. 

There was zero point in keeping Thomas, especially when he could have returned much-needed draft capital after the team traded five total picks at the deadline, if he isn't going to play a much larger role in the offense moving forward. 

The Titans give up 258 yards per game through the air, the second-most in the NFL. If Thomas can’t make an impact against Tennessee, who can he make an impact against?