With one of the biggest fixtures on the Premier League calendar fast approaching, Liverpool will have to navigate the encounter without two of their attacking options, leaving Iraola with another selection headache at precisely the wrong time.

Speaking during his pre-match press conference on Friday, the Liverpool head coach provided an update on both players, offering some reassurance over the severity of their injuries while confirming neither would recover in time for Sunday's contest.

On Gakpo, Iraola explained:

"Cody has an ankle injury and had some before in his career and it's a matter of him dealing with the pain. If you twist your ankle, it was a really bad tackle I think."

The Dutch international's absence is particularly frustrating given his versatility across Liverpool's frontline. Comfortable operating from the left or through the middle, Gakpo offers a different attacking dimension, combining intelligent movement with an eye for goal.

His ability to cut inside, link play and create opportunities could have proved valuable against a Manchester City side that will undoubtedly test Liverpool's attacking organisation.

Meanwhile, Isak is dealing with a thigh problem, although Iraola was quick to play down fears of a lengthy spell on the sidelines.

The Liverpool boss added:

"Alex has a thigh injury. It's not a massive injury, a small one, but it's an injury. They don't look long term. We will be analysing day to day but won't be ready for Sunday."

That assessment will come as something of a relief to Liverpool fans, particularly given the importance of keeping their attacking players available during a demanding period of the season.

Isak's absence removes another significant threat from Liverpool's attacking front. The Swedish international possesses the pace, technical ability and composure to trouble even the most organised defensive units.

Against opponents of City's calibre, having a forward capable of creating something from seemingly nothing can often make the difference.

For Iraola, the immediate challenge is finding the right attacking combination without compromising Liverpool's ability to press, retain possession and threaten in transition.

The encouraging news is that neither injury currently appears to be a long-term concern. However, the manager's day-to-day assessment suggests there is still uncertainty surrounding exactly when the pair will return.

For now, Liverpool must focus on Manchester City with the players available.

And in a fixture where the smallest margins can decide everything, losing two attacking options before a ball has even been kicked is far from ideal.

What will the result be in Sunday's clash with Manchester City with the strikeforce out? Leave your thoughts and comments below.