The Los Angeles Rams had to gut it out to get a win against the Philadelphia Eagles on Sunday, and now the team sits at 2-2. The issue is that they now face a strong 3-1 Buffalo Bills team on Monday night.

Losing a few more games might all but doom the Rams' chances of getting the NFC crown down the stretch, making a victory against Buffalo that much more important.

Here are four bold predictions for the matchup.

Rams quarterback Matthew Stafford has been off, to say the least. After throwing six interceptions over four weeks, there are some big concerns about his accuracy. 

Stafford rifled off 317 yards against the Eagles, but no touchdowns. Now, he will find his timing and deliver three touchdowns against the Bills.

Puka Nacua came back in a big way, securing 125 yards. While it was a quieter game for Davante Adams, both will work in tandem to bring this offense back to its prominence.

Aaron Donald missed Week 4 due to a back issue, and that may have been why his Week 3 performance was not as impressive. After some extended time to heal, he will come out like a cannon on Monday.

Donald needs to notch a sack in 2026, and he will do so against Bills quarterback Josh Allen. One sure-fire way to throw Buffalo off is by getting after Allen, so expect the Rams' pass rush to want to push that envelope. 

The Rams have pulled back from their split-carry plan, as running back Kyren Williams has been fantastic. He continues to run hard and be effective in the passing game, which is what the Bills will make a point of stopping.

With the attention being on Williams, Blake Corum will come out with his tough-run style to bring back some attention on his end. 

Most defenses can contain one back if they plan to do so, but the Rams have two capable backs that make planning very hard.

From pinning the Los Angeles back due to fielding punts at the wrong time, to kicker Harrison Mevis missing, the special teams in 2026 has been a disaster.

Rams head coach Sean McVay is not one to allow things to snowball. He may have spoken about being out of rhythm, but he will get the team into shape. 

This means ensuring that Bubba Ventrone and the special teams unit figures out their miscues.