Oct 1, 2026 9:40 PM

The Buffalo Bills have been given a minor advantage over the Patriots in a new prediction.

After barely surviving the Los Angeles Chargers last week, the Buffalo Bills are now getting ready to take on the New England Patriots.

Buffalo comes into the game with a record of 3-0, with the team looking to build upon what has been a strong start to the season. While the team didn't play well at all last week against the Chargers, the Bills were able to come away with the win.

Good teams aren't always going to play well, but the best teams still find a way to win games. Buffalo will now be looking for ways to clean things up against New England, but the Bills will need to be careful.

New England is coming into this game sitting with a record of 1-2 for the new season, and they are coming off a tough blowout loss. The Patriots were rocked by the Jacksonville Jaguars 35-6 a week ago, and they are coming to right the ship against the Bills.

Ahead of the game, Bleacher Report NFL analysts Gary Davenport, Brad Gagnon, Kris Knox, Moe Moton, Brent Sobleski, Wes O'Donnell, and Ian Hanford all made picks for the game. Of these experts, just four of the seven predicted the Bills to take down the Patriots this week at home.

Davenport, Hanford, Knox, and Sobleski were the four to take Buffalo this week. Buffalo was given the sight edge of 4-3 over New England in the prediction before the game.

With the Patriots having a sense of desperation heading into the contest, Buffalo will need to be ready to go. The Bills are going to want to bury their AFC East rivals early on in the contest, pushing them farther down the standings.

But if the Bills play like they did against the Chargers, it could be a long game all around. The last thing that Buffalo wants to do is give the Patriots any sort of life, so this group will need to come in with a strong mentality from the jump.

Much of this starts with the offense, namely quarterback Josh Allen, who threw multiple interceptions against Los Angeles. Allen is the engine for the Bills, and this entire team goes as he does.

Against a tough New England defense, Allen will try to get back on track, while helping his team move to 4-0 on the new season. Buffalo will have its hands full with the Patriots, but playing at home could also give them another advantage in the game.

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