PSV Eindhoven suffered a damaging setback in the Eredivisie on Saturday, losing 2-1 to ADO Den Haag after conceding a stoppage-time winner at the WerkTalent Stadion.

Peter Bosz’s side initially looked on course for a routine victory when Sven Mijnans fired them ahead in the 21st minute. However, the match turned dramatically after Mijnans received a second yellow card shortly before half-time, leaving PSV to play the remainder of the contest with 10 men.

ADO capitalised on their numerical advantage after the break, with Juho Kilo’s deflected effort restoring parity before substitute Matej Sin headed home the winner in the 93rd minute.

The defeat leaves PSV third in the table and unable to take advantage of the opportunity to move top. With Guus Til also forced off through injury and Mijnans suspended for the upcoming clash against Feyenoord, the result could have consequences beyond the immediate loss of points.

Here are three key lessons from PSV’s disappointing afternoon.

PSV travelled to The Hague already short of attacking options, with several recognised forwards unavailable through injury. The situation deteriorated further when Til was forced off in the 40th minute after landing awkwardly on his back and neck during an aerial challenge.

The 28-year-old had been influential in the opening stages, setting up Mijnans for the opening goal with a cross from the right. His departure forced Bosz to introduce 17-year-old Mikkel Bro Hansen earlier than planned.

PSV still created opportunities despite their reduced numbers. Substitute Amir Bouhamdi struck the crossbar following a quick counter-attack, while Bro Hansen also threatened from the flank. However, the visitors lacked the cutting edge required to find a second goal.

The concern now extends to the coming fixtures. Til’s availability remains uncertain, while Mijnans will miss next weekend’s meeting with Feyenoord through suspension.

With PSV already struggling for depth up front, losing two players who had been central to their makeshift attacking setup leaves Bosz with another selection problem to solve.

Mijnans had given PSV the perfect start, producing an excellent first-time finish into the top corner after Til’s delivery. Yet his contribution ultimately became a major factor in the defeat.

Already booked for pulling Matteo Waem’s shirt, the midfielder received a second yellow card in the 43rd minute after arriving late with a sliding tackle on Pascal Mulder.

The dismissal was particularly costly because PSV had controlled much of the opening period and looked capable of extending their lead. Instead, Bosz’s team had to reorganise before half-time and defend with 10 men for the remainder of the match.

ADO responded by pushing forward more aggressively after the interval. Kilo’s powerful effort in the 56th minute took a deflection off Mauro Júnior and beat goalkeeper Matej Kovář, giving the hosts renewed belief.

Mijnans’ sending-off was not the only reason PSV lost, but it fundamentally changed the contest. His suspension also means Bosz must find another solution for the Feyenoord fixture, compounding an already difficult week.

PSV’s defeat was particularly damaging because ADO had entered the match without a league victory this season. The hosts had struggled defensively, but the red card gave them an opportunity to turn the game around.

Kilo’s equaliser lifted the home side, who continued to press for a winner. PSV still threatened on the counter-attack, with Bouhamdi hitting the crossbar, but they could not regain control.

The decisive moment arrived in the 93rd minute. Rottier played the ball across the penalty area following a free-kick, allowing substitute Sin to head home and complete ADO’s comeback.

For PSV, the late goal capped a second consecutive away defeat across all competitions, following their Champions League loss to RB Leipzig. It also denied them the chance to climb to the top of the Eredivisie table.

ADO, meanwhile, secured their first league win of the season and provisionally moved up to 16th.

Bosz’s side now face renewed questions over their ability to manage difficult away matches, particularly when injuries and disciplinary mistakes disrupt their plans. With Feyenoord next on the domestic schedule, PSV must respond quickly or risk allowing their rivals to strengthen their position in the title race.