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    Jake Arthur
    Jake Arthur
    Oct 10, 2025, 20:18
    Updated at: Oct 10, 2025, 20:18

    INDIANAPOLIS, Ind. — The Indianapolis Colts received a largely clean bill of health on Friday following their final practice of the week ahead of their matchup with the Arizona Cardinals this Sunday.

    Colts head coach Shane Steichen announced that starting wide receiver Alec Pierce cleared the concussion protocol and is "ready to roll." Steichen ruled out backup running back Tyler Goodson (groin) and starting slot cornerback Kenny Moore II (Achilles) for Sunday, while no other players contain injury designations entering the weekend.

    The Cardinals have to wait and see if quarterback Kyler Murray (foot) is able to play, after he injured his foot in last week's loss to the Tennessee Titans. Murray didn't practice on Wednesday or Thursday, and was a limited participant on Friday. Cardinals head coach Jonathan Gannon told reporters that if Murray is healthy enough to play, he'll play.

    Here's how each team's health is shaping up ahead of Sunday afternoon's battle:

    COLTS

    WEDNESDAY

    • Did Not Participate — RB Tyler Goodson (groin), DE Tyquan Lewis (illness), CB Kenny Moore II (Achilles), OT Braden Smith (rest)
    • Full Participant — WR Alec Pierce (concussion), DT Grover Stewart (biceps)

    THURSDAY

    • Did Not Participate — RB Tyler Goodson (groin), CB Kenny Moore II (Achilles), DT Grover Stewart (biceps/rest)
    • Full Participant — DE Tyquan Lewis (illness), WR Alec Pierce (concussion), OT Braden Smith (rest)

    FRIDAY

    • Did Not Participate — DT DeForest Buckner (rest), RB Tyler Goodson (groin), CB Kenny Moore II (Achilles), CB Charvarius Ward Sr. (rest)
    • Limited Participant — DE Samson Ebukam (rest)
    • Full Participant — DE Tyquan Lewis (illness), WR Alec Pierce (concussion), OT Braden Smith (rest), DT Grover Stewart (biceps/rest)

    OUT — RB Tyler Goodson (groin), CB Kenny Moore II (Achilles)

    With Pierce back, it puts Ashton Dulin back into a reserve role, and AD Mitchell in question of whether he'll be made active.

    Goodson remains out after suffering a groin injury two weeks ago against the Los Angeles Rams. He did not return to that game and has not practiced since. The Colts called up running back Ameer Abdullah from the practice squad in Goodson's spot last week.

    With Moore still not practicing, it obviously puts his status in doubt for this week. His backup, Mike Hilton, suffered a shoulder injury last week that landed him on the Practice Squad Injured Reserve list, so it would likely be Chris Lammons starting in the slot for the Colts this Sunday.

    CARDINALS

    WEDNESDAY

    • Did Not Participate — OT Kelvin Beachum (rest), QB Kyler Murray (foot), DT Darius Robinson (pectoral)
    • Limited Participant — G Evan Brown (hamstring), G Will Hernandez (knee), CB Will Johnson (groin), WR Zay Jones (knee), CB Max Melton (hamstring), LB Cody Simon (knee), OT Jonah Williams (foot), LB Mack Wilson (ankle)

    THURSDAY

    • Did Not Participate — QB Kyler Murray (foot), DT Darius Robinson (pectoral)
    • Limited Participant — G Evan Brown (hamstring), P Blake Gillikin (back), G Will Hernandez (knee), CB Will Johnson (groin), WR Zay Jones (knee), CB Max Melton (hamstring), LB Cody Simon (knee), OT Jonah Williams (foot), LB Mack Wilson (ankle)
    • Full Participant — OT Kelvin Beachum (rest)

    FRIDAY

    • Did Not Participate — DT Calais Campbell (rest), P Blake Gillikin (back), DT Darius Robinson (pec)
    • Limited Participant — WR Zay Jones (knee), CB Max Melton (hamstring), QB Kyler Murray (foot), LB Cody Simon (knee), LB Mack Wilson (ankle)
    • Full Participant — G Evan Brown (hamstring), G Will Hernandez (knee), CB Will Johnson (groin), OT Jonah Williams (foot)

    QUESTIONABLE — P Blake Gillikin (back), WR Zay Jones (knee), CB Max Melton (hamstring), QB Kyler Murray (foot), LB Cody Simon (knee), LB Mack Wilson (ankle)

    OUT — DT Darius Robinson (pec)

    Murray is the most significant development here as Arizona's starting quarterback and one of their top players. If he's unable to play, it'll be a familiar face starting against the Colts, former Colts quarterback Jacoby Brissett, who was with the team from 2017-20.

    Robinson missed last week's game with his pec injury as well, so they'll continue to be without one of their promising young linemen.

    The Colts and Cardinals play this Sunday at Lucas Oil Stadium in Indianapolis at 1:00 p.m. E.T. on FOX.


    Jake Arthur has been covering the Indianapolis Colts for over a dozen years and is a member of the PFWA. He's one half of the Locked On Colts podcast and has worked for the Colts' official website, On SI, and more. You can follow him on X @JakeArthurNFL.